Gentle Tissue Contraction3,4,5,6,7,8,9

Renuvion has been shown to provide controlled coagulation and therefore contraction of soft tissue.3,4,5,6,7,11 With Renuvion, you can achieve more optimal results than with liposuction alone. It can also be an appealing alternative for patients who are seeking a faster, minimally invasive procedure with less risk, faster recovery time, and less scarring.10,11,12,13,14,15,16,17

Device Overview

What Is Renuvion?

Renuvion cosmetic technology delivers a proprietary blend of helium plasma and radiofrequency energy to gently contract tissue with exceptional control and precision.3,4,5,6,7,8,9 A product of years of scientific research, testing, and refinement, the Renuvion system is also an all-in-one electrosurgical unit with full monopolar and bipolar functions, allowing you to save time and space with a single capital investment.

How It Works

Fast, Innovative Tissue Contraction

The optimal temperature for subdermal tissue contraction is 85°C, but most standard monopolar and bipolar radiofrequency devices can’t reach this temperature quickly enough without causing a concerning rise in skin temperature.3,4,5,6,7,17,18 Renuvion, however, heats to 85°C safely with minimal thermal spread and cools to baseline temperatures in less than a second.11 This maximizes tissue contraction with a shorter application time. Entry points are very small, resulting in less pain, shorter recovery, and minimal scarring.12,14,15


Meeting Patients’ Needs

The Renuvion system has received a general clearance for the cutting, coagulation and ablation soft tissue during open surgical procedures. Renuvion can be used with tumescent or general anesthesia. In a survey of 100 Physician Users, it was reported that Renuvion has been used on a variety of body areas15, including:

• Neck
• Arms
• Abdomen
• Thighs
• Back
• Knees
• Chest
• Buttocks
• Breast

Happy Patients. More Revenue.

Renuvion enables you to deliver a better patient experience,
expand your capabilities, and attract more patients.1,2


Patient Benefits

Minimally invasive11
Shorter Procedure14,15,17,18,19
Less Pain12,14,15
Shorter Recovery Time12,14,15
Visible Results Quickly14,15,17
Long-Term Results14,15,17
Less Risk of Complications12,15*

*compared to more invasive surgery


Practice Benefits

Competitive Differentiator
New Source of Revenue1,2
Increased Patient Leads2
Higher Patient Satisfaction14,16
Standalone Procedure or Adjunct to Liposuction
Consistent Outcomes13
Industry Leading 4-Year Warranty

Ready to try Renuvion and revitalize your practice?

The Renuvion system is intended to be used with compatible electrosurgical generators for the delivery of radiofrequency energy and/or helium plasma to cut, coagulate and ablate soft tissue during open surgical procedures. The Apyx® Plasma/RF Handpiece (APR HP) is a sterile, single use electrosurgical (monopolar) device intended to be used in conjunction with compatible generators for the percutaneous delivery of radiofrequency energy and/or helium plasma for cutting, coagulation and ablation of soft tissue.

The Renuvion system has received a general clearance and has not been determined to be safe or effective for use in any specific indication or anatomical location. Apyx Medical does not promote its general clearance products for any specific surgical specialty or subspecialty.

Risk associated with the use of the Renuvion system for subdermal coagulation may include: Helium embolism into the surgical site due to inadvertent introduction into the venous or arterial blood supply system, unintended burns (deep or superficial), pneumothorax, temporary or permanent nerve injury, ischemia, fibrosis, infection, pain, discomfort, gas buildup resulting in temporary and transient crepitus or pain, bleeding, hematoma, seroma, subcutaneous induration, pigmentation changes, increased healing time, unsatisfactory scarring, asymmetry and/or unacceptable cosmetic result. There may be additional risks associated with the use of other devices along with Renuvion and there may be an increased risk for patients who have undergone prior surgical or aesthetic procedures in the treatment area. As with any procedure, individual results may vary. As with all energy devices there are inherent risks associated with its use, refer to the IFU for further information.


  1. The Value of Renuvion- A Case Study with Kyle Song, MD. MM00210.00 0819 –
  2. The Value of Renuvion- A Case Study with Paul G. Ruff IV, MD. MM00209.00 0819 –
  3. Feldman LS, et al. (eds). The SAGES Manual on the Fundamental Use of Surgical Energy (FUSE), ISBN 978‐1‐4614‐2073‐6.
  4. Chen SS, Wright NT, Humphrey JD. Heat-induced changes in the mechanics of a collagenous tissue: isothermal free shrinkage. Journal of Biomechanical Engineering 1997:109:372-378.
  5. McDonald MB. Conductive Keratoplasty: A Radiofrequency-based Technique for the Correction of Hyperopia. Trans Am Ophthalmol Soc 2005;103:512-536.
  6. Chen SS, Humphrey JD. Heat-induced changes in the mechanics of a collagenous tissue: pseudoelastic behavior at 37° C. J Biomech 1998;31:211-216.
  7. Wright NT, Humphrey JD. Denaturation of collagen during heating: An irreversible rate process. Annu Rev Biomed Eng; 2002;4:109-128.
  8. Ramsdell WM. Fractional Carbon Dioxide Laser Resurfacing. Semin Plast Surg 2012;26:125-130.
  9. Masghati S, Pedroso J, Gutierrez M, Stockwell E, Volker W, Howard DL. Comparative Thermal Effects of J-Plasma®, Monopolar, Argon, and Laser Electrosurgery in a Porcine Tissue Model. Surgical Technology International, 2019;34:1-5. PMID: 30825320.
  10. American Society of Plastic Surgeons. Plastic Surgery Statistics Report. 2019.
  11. Duncan DI and Roman S. Helium Plasma Subdermal Tissue Contraction Method of Action. Biomed J Sci & Tech Res 31(2)-2020. BJSTR. MS.ID.005075.
  12. Dayan S. Aesthetic evolution drives birth of minimally invasive surgery subgroup. J Cosmet Dermatol. 2019 Jun 26. doi: 10.1111/jocd.13057. Epub ahead of print. PMID: 31243875.
  13. Doolabh, V, Ruff, P. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews. 2020; 1– 8.
  14. Kluska M, Nasseri S, Bobrovnikov V. Helium Plasma Versus Radiofrequency for Energy-Enhanced Liposuction: A Prospective Single-Blind Pilot Study (White Paper). 2020.
  15. Renuvion Physician Survey Results, MM0317.00 0620 –
  16. Ruff PG, Doolabh V, Zimmerman EM, Gentile RA. Safety and efficacy of helium plasma for subdermal coagulation. Dermatological Reviews. 2020;1-7.
  17. Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2019; 2(1):89-95.
  18. Diane Irvine Duncan (March 8th 2019). Helium Plasma-Driven Radiofrequency in Body Contouring, The Art of Body Contouring, Alexandro Aguilera, IntechOpen, DOI: 10.5772/intechopen.84207. Available from:
  19. Neinstein R, Funderburk C. Advances in Skin Tightening with Liposculpture: Plasma Technology Versus Radiofrequency. Advances in Cosmetic Surgery 2020;3(1):173-188.