A Matter of Energy

  • Higher temperatures cause greater tissue contraction (figure 1)1,2,3,4,5
    • Collagen contracts predictably when exposed to heat, and higher temperatures cause greater contraction in less time
    • To be effective, subdermal tissue must be heated to a minimum of 65°C for significant tissue contraction to occur
  • Standard radiofrequency devices can’t consistently heat beyond 65°C6,7,8
    • 85°C is a more optimal temperature for tissue contraction, but most standard monopolar and bipolar radiofrequency devices can’t reach this temperature quickly enough without causing a concerning rise in skin temperature
  • Renuvion® heats to 85°C safely, allowing for optimal tissue contraction and faster procedure times1,2,3,4,5,6,7,8,9
    • Renuvion heats up to 85°C just long enough to cause maximum contraction of collagen and can cool back down to baseline temperatures in less than a second (figure 2)
    • The rapid heating and cooling of tissue allows for shorter application time

Figure 1

Figure 2

Safety By Design

  • The unique Renuvion energy— helium plasma and proprietary RF — allows for precisely controlled delivery of heat to tissue, with minimal thermal diffusion6,10,11
  • Rapid heating with near-instantaneous cooling (figure 3) allows for shorter duration of activation, and therefore less diffusion of heat to the skin6
  • Studies show that when using the recommended techniques, temperature at the surface of the skin does not rise by more than 4°C, making cumbersome external temperature monitoring unnecessary (figure 4)6

Figure 3 – Illustration highlighting the heating of the fibroseptal network to the point of instant contraction (85°C), while maintaining safe skin temperatures (≤41°C)

Figure 4 – Thermal image of the thigh of a 52 year-old female shows minimal rise in skin temperatures during the 4th pass with Renuvion

Built On Proven Technology

One of the most exciting advancements in energy technology in the past 20 years, the Renuvion system combines the unique properties of cold helium plasma with the efficiency of RF energy. This synergy enables a high degree of precision, and always with minimal thermal effect to surrounding tissue.6

Renuvion has FDA clearance for the cutting, coagulation and ablation of soft tissue during open and laparoscopic surgical procedures.12

    1. Feldman LS, et al. (eds). The SAGES Manual on the Fundamental Use of Surgical Energy (FUSE), ISBN 978-1-4614-2073-6.
    2. Chen SS, Wright NT, Humphrey JD. Heat-induced changes in the mechanics of a collagenous tissue: isothermal free shrinkage. Journal of Biomechanical Engineering 1997:109:372-378.
    3. McDonald MB. Conductive Keratoplasty: A Radiofrequency-based Technique for the Correction of Hyperopia. Trans Am Ophthalmol Soc 2005;103:512-536.
    4. Chen SS, Humphrey JD. Heat-induced changes in the mechanics of a collagenous tissue: pseudoelastic behavior at 37° C. J Biomech 1998;31:211-216.
    5. Wright NT, Humphrey JD. Denaturation of collagen during heating: An irreversible rate process. Annu Rev Biomed Eng; 2002;4:109-128.
    6. Duncan DI and Roman S. Helium Plasma Subdermal Tissue Contraction Method of Action. Biomed J Sci & Tech Res 31(2)-2020. BJSTR. MS.ID.005075.
    7. Diane Irvine Duncan (March 8th 2019). Helium Plasma-Driven Radiofrequency in Body Contouring, The Art of Body Contouring, Alexandro Aguilera, IntechOpen, DOI: 10.5772/intechopen.84207. Available from: https://www.intechopen.com/books/the-art-of-body-contouring/helium-plasma-driven-radiofrequency-in-body-contouring.
    8. Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2019; 2(1):89-95.
    9. Kluska M, Nasseri S, Bobrovnikov V. Helium Plasma Versus Radiofrequency for Energy-Enhanced Liposuction: A Prospective Single-Blind Pilot Study (White Paper). 2020. https://www.renuvion.com/clinical/.
    10. Ramsdell WM. Fractional Carbon Dioxide Laser Resurfacing. Semin Plast Surg 2012;26:125-130.
    11. Masghati S, Pedroso J, Gutierrez M, Stockwell E, Volker W, Howard DL. Comparative Thermal Effects of J-Plasma®, Monopolar, Argon, and Laser Electrosurgery in a Porcine Tissue Model. Surgical Technology International, 2019;34:1-5. PMID: 30825320.
    12. Renuvion/J-Plasma® has received a general clearance and has not been determined to be safe or effective for use in any specific procedures for the treatment of any specific conditions.
The Renuvion System