Why Renuvion?

Renuvion provides precise tissue contraction2,3,4,5,6,8 and can be used for those seeking optimal results without excisional surgery.9 Delivering an innovative combination of radiofrequency energy and helium plasma, Renuvion safely heats to the optimal temperature for maximum tissue contraction and cools down in less than a second.2,3,4,5,6,7 This allows you to achieve better results with better control and precision in less time.8,9,10

Using this proprietary technology from Apyx® Medical, many practices have been able to augment their services, attract more patients, schedule more procedures, and boost revenue.



Discover what’s possible with Renuvion and see why this technology is so innovative.

For Physicians

Find out how Renuvion can help you grow your practice, expand your patient population, and deliver better outcomes.9,10

Advantages of Renuvion


Less Invasive

Renuvion is used in a minimally invasive procedure through small entry points to contract tissue.2,3,4,5,6,7 Incisional scars are very minor compared to traditional excisional surgery.1


Less Downtime

The procedure can be performed while awake with a local anesthetic or while the patient is asleep. Recovery time is shorter compared to more invasive treatments and alternative minimally invasive RF technology.1,9


Predictable Performance

Doctors report that Renuvion is a safe and predictable technology.9

What People Are Saying About Renuvion

About Apyx Medical

Apyx Medical has earned the trust of practices and hospitals around the world by continuously developing, testing, and refining transformative solutions that meet physicians’ evolving needs and elevate patients’ lives.

Success is driven not by bold marketing claims, but through scientific research, market testing, and constant improvement. This is how Apyx Medical develops advanced energy technology – game-changing solutions that enable doctors to do things they couldn’t do before.

Learn More About Renuvion:

The Renuvion system is intended to be used with compatible electrosurgical generators for the delivery of radiofrequency energy and/or helium plasma to cut, coagulate and ablate soft tissue during open surgical procedures. The Apyx Plasma/RF Handpiece (APR HP) is a sterile, single use electrosurgical (monopolar) device intended to be used in conjunction with compatible generators for the percutaneous delivery of radiofrequency energy and/or helium plasma for cutting, coagulation and ablation of soft tissue.

The Renuvion system has received a general clearance and has not been determined to be safe or effective for use in any specific indication or anatomical location. Apyx Medical does not promote its general clearance products for any specific surgical specialty or subspecialty.

Risk associated with the use of the Renuvion system for subdermal coagulation may include: Helium embolism into the surgical site due to inadvertent introduction into the venous or arterial blood supply system, unintended burns (deep or superficial), pneumothorax, temporary or permanent nerve injury, ischemia, fibrosis, infection, pain, discomfort, gas buildup resulting in temporary and transient crepitus or pain, bleeding, hematoma, seroma, subcutaneous induration, pigmentation changes, increased healing time, unsatisfactory scarring, asymmetry and/or unacceptable cosmetic result. There may be additional risks associated with the use of other devices along with Renuvion and there may be an increased risk for patients who have undergone prior surgical or aesthetic procedures in the treatment area. As with any procedure, individual results may vary. As with all energy devices there are inherent risks associated with its use, refer to the IFU for further information.


  1. Mohiuddin K, Swanson SJ. Maximizing the benefit of minimally invasive surgery. J Surg Oncol. 2013 Oct;108(5):315-9. doi: 10.1002/jso.23398. Epub 2013 Aug 23. PMID: 24037974.
  2. Feldman LS, et al. (eds). The SAGES Manual on the Fundamental Use of Surgical Energy (FUSE), ISBN 978‐1‐4614‐2073‐6.
  3. Chen SS, Wright NT, Humphrey JD. Heat-induced changes in the mechanics of a collagenous tissue: isothermal free shrinkage. Journal of Biomechanical Engineering 1997:109:372-378.
  4. McDonald MB. Conductive Keratoplasty: A Radiofrequency-based Technique for the Correction of Hyperopia. Trans Am Ophthalmol Soc 2005;103:512-536.
  5. Chen SS, Humphrey JD. Heat-induced changes in the mechanics of a collagenous tissue: pseudoelastic behavior at 37° C. J Biomech 1998;31:211-216.
  6. Wright NT, Humphrey JD. Denaturation of collagen during heating: An irreversible rate process. Annu Rev Biomed Eng; 2002;4:109-128.
  7. Duncan DI and Roman S. Helium Plasma Subdermal Tissue Contraction Method of Action. Biomed J Sci & Tech Res 31(2)-2020. BJSTR. MS.ID.005075.
  8. Masghati S, Pedroso J, Gutierrez M, Stockwell E, Volker W, Howard DL. Comparative Thermal Effects of J-Plasma®, Monopolar, Argon, and Laser Electrosurgery in a Porcine Tissue Model. Surgical Technology International, 2019;34:1-5. PMID: 30825320.
  9. Renuvion Physician Survey Results, MM0317.01 0422 – https://www.renuvion.com/wp-content/uploads/2022/05/renuvion-physician-survey-results-brochure_mm0317.01_050222.pdf.
  10. Ruff PG, Doolabh V, Zimmerman EM, Gentile RA. Safety and efficacy of helium plasma for subdermal coagulation. Dermatological Reviews. 2020;1-7. https://doi.org/10.1002/der2.34.